Ischemic conditioning ameliorated hypertension and vascular remodeling of spontaneously hypertensive rat via inflammatory regulation
it detects initial lipid peroxidation signals and amplifies the peroxidation cascade through ACSL4 phosphorylation, thereby positively regulating ferroptosis ( APOE gene polymorphism (2/3/4) profoundly influences ferroptosis susceptibility and neurodegenerative progression by remodeling neural lipid metabolism networks
doi: 10.3389/fnut.2025.1754492 Received 26 November 2025 Revised 20 December 2025 Accepted 24 December 2025 Published 21 January 2026 Volume 12 - 2025 Edited by Javier Diaz-Castro, University of Granada, Spain Reviewed by Mahsa Rezazadegan, Isfahan University of Medical Sciences, Iran Soroush Taherkhani, Iran University of Medical Sciences, Iran Updates Copyright 2026 Poon, Li, Schweitzer and Akefe
Taken together, NAC supplementation improved intestinal function and attenuated intestinal autophagy in -CG-challenged piglets